pathway-enrichment

SAFE max severity SAFESkillSpector Caution 15 registry K-Dense-AI last scanned 1 scan

No security findings. Scanned 1 time, most recently 2026-10-21.

Second scanner: NVIDIA SkillSpector

Independent static run, no language model, over the same files as the Cisco scan above. How the two scanners compare across the whole corpus: Two scanners, one corpus.

What this skill does

Performs pathway and gene-set enrichment analysis on gene lists or ranked gene data and interprets the results. Used when the user has a set of genes (differentially expressed genes from PyDESeq2/Scanpy, CRISPR-screen hits, cluster marker genes, proteomics hits) and wants to know which biological pathways, GO terms, or gene sets are over-represented or enriched. Covers over-representation analysis (ORA / Enrichr / Fisher / hypergeometric), ranked Gene Set Enrichment Analysis (GSEA / preranked), single-sample scoring (ssGSEA/GSVA), and functional profiling via gseapy, g:Profiler, Enrichr…

Package
6 files, 63 KB
SKILL.md
2032 words, 12+ sections
Code
Python (1)
License
MIT
Compatibility
Requires Python 3.12+ with gseapy 1.3.1, numpy, pandas and matplotlib. Optional gprofiler-official, mygene and lxml for online mapping/catalogs. Online queries need network access; local GMT workflows run offline.

SKILL.md covers: Pathway Enrichment · Overview · When to Use This Skill · Choosing the Right Method · Setup · gseapy pulls pandas, numpy, scipy, matplotlib. Network access is needed for · Enrichr, g:Profiler, and MSigDB downloads. For fully offline ORA, use a local · GMT file with gp.enrich() (see references/gseapy.md). · Quick Start · ORA on a hit list (gseapy + Enrichr) · Match the library organism and identifier namespace; map aliases explicitly. · Keep original spelling: capitalization is not gene-ID or orthology mapping.

Findings

No findings. SAFE

What is in the package

FileKindSize
SKILL.mddoc16 KB
references/databases-and-gene-sets.mddoc8.8 KB
references/gseapy.mddoc9.6 KB
references/interpretation.mddoc7.3 KB
references/verified-api.mddoc8.1 KB
scripts/run_enrichment.pyscript13 KB

External hosts referenced

github.com www.gsea-msigdb.org biit.cs.ut.ee maayanlab.cloud docs.gsea-msigdb.org arxiv.org decoupler.scverse.org gseapy.readthedocs.io pypi.org data.broadinstitute.org docs.mygene.info doi.org export.arxiv.org mygene.info www.ensembl.org

Hostnames that appear in the skill's files. Referencing a host is not a finding; compare against the findings above and the skill's stated purpose.

Package contents recorded 2026-10-22 at commit 593377bb0487. The scan above ran against the version current at scan time; the two can differ if the skill has since been updated.

What we checked

What we did not check

Sources