alphagenome

SAFE max severity LOWSkillSpector Caution 39 registry K-Dense-AI last scanned 1 scan

Verdict safe, but 1 finding (1 low), mainly unauthorized tool use. Most recent scan 2026-10-21.

Second scanner: NVIDIA SkillSpector

Independent static run, no language model, over the same files as the Cisco scan above. How the two scanners compare across the whole corpus: Two scanners, one corpus.

What this skill does

Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), scores variants or scans windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and builds Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind…

Package
8 files, 118 KB
SKILL.md
1987 words, 12+ sections
Code
Python (4)
Allowed tools
Read Write Edit Bash
License
MIT
Compatibility
Python 3.10+ with the alphagenome package (0.9.0 or later for the Atlas client; brings numpy, pandas, anndata, grpcio). Network access to gdmscience.googleapis.com:443 and a free non-commercial AlphaGenome API key in ALPHAGENOME_API_KEY (ALPHA_GENOME_API_KEY also read). Human data is GRCh38 only; mouse is mm10 (model only).

SKILL.md covers: AlphaGenome and the AlphaGenome Atlas · When to use which · Setup · The coordinate contract · Atlas workflow · 1. Rank with AVI · 2. Resolve the mechanism by track · 3. Send the reader to the portal · In Python · Model workflow · Score variants the Atlas does not hold · Predict tracks and mutagenise

Findings

LOW Code uses search/grep patterns but Grep tool not in allowed-tools Unauthorized Tool Usestatic

Skill restricts tools to ['Read', 'Write', 'Edit', 'Bash'] but code uses regex search patterns

SKILL.md

Remediation: Add 'Grep' to allowed-tools or remove regex search operations

What is in the package

FileKindSize
SKILL.mddoc17 KB
references/atlas.mddoc17 KB
references/interpretation.mddoc8.4 KB
references/model-api.mddoc14 KB
scripts/_common.pyscript19 KB
scripts/atlas_link.pyscript7.3 KB
scripts/atlas_query.pyscript23 KB
scripts/score_variants.pyscript11 KB

External hosts referenced

github.com www.alphagenomedocs.com deepmind.google.com alphagenome.google storage.googleapis.com arxiv.org doi.org deepmind.google docs.cloud.google.com export.arxiv.org pypi.org

Hostnames that appear in the skill's files. Referencing a host is not a finding; compare against the findings above and the skill's stated purpose.

Environment variables referenced

AVI_SCORE_FEATURE_IMPORTANCE ALPHA_GENOME_API_KEY

Package contents recorded 2026-10-22 at commit 593377bb0487. The scan above ran against the version current at scan time; the two can differ if the skill has since been updated.

What we checked

What we did not check

Sources