genomic-coordinates

SAFE max severity LOWSkillSpector Caution 24 registry K-Dense-AI last scanned 1 scan

Verdict safe, but 1 finding (1 low), mainly unauthorized tool use. Most recent scan 2026-10-21.

Second scanner: NVIDIA SkillSpector

Independent static run, no language model, over the same files as the Cisco scan above. How the two scanners compare across the whole corpus: Two scanners, one corpus.

What this skill does

Converts genomic intervals between coordinate conventions, normalises and compares variant representations, and detects assembly or contig-naming mismatches before they corrupt an analysis. Used whenever coordinates cross a format, tool, or assembly boundary - converting between BED, GFF/GTF, VCF, SAM/BAM, WIG, PSL, genePred, Picard interval_list, or region strings; reconciling 0-based half-open with 1-based inclusive; left-aligning or trimming indels; checking whether two variant records describe the same change; mapping genomic to transcript, CDS, or protein positions; auditing a…

Package
10 files, 119 KB
SKILL.md
1559 words, 12+ sections
Code
Python (5)
Allowed tools
Read Write Edit Bash
License
MIT
Compatibility
Requires Python 3.11+. Scripts use only the standard library - no third-party packages and no network access. Variant normalisation needs an uncompressed reference FASTA with exact contig names; .fai enables indexed access. Without .fai the entire FASTA is loaded into memory.

SKILL.md covers: Genomic Coordinates · When to use · The rule · The two conversions · Which format is which · Variants are not intervals · Check the assembly before trusting a join · Audit a file against its own format · Transcript, CDS, and protein positions · Reporting results · Verified scope · References

Findings

LOW Code uses search/grep patterns but Grep tool not in allowed-tools Unauthorized Tool Usestatic

Skill restricts tools to ['Read', 'Write', 'Edit', 'Bash'] but code uses regex search patterns

SKILL.md

Remediation: Add 'Grep' to allowed-tools or remove regex search operations

What is in the package

FileKindSize
SKILL.mddoc12 KB
references/format-conventions.mddoc12 KB
references/reference-builds.mddoc7.8 KB
references/transcript-coordinates.mddoc8.2 KB
references/variant-representation.mddoc7.9 KB
scripts/_common.pyscript14 KB
scripts/audit_intervals.pyscript21 KB
scripts/check_contigs.pyscript17 KB
scripts/convert_coords.pyscript7.4 KB
scripts/normalize_variant.pyscript11 KB

External hosts referenced

hgvs-nomenclature.org samtools.github.io github.com bedtools.readthedocs.io hgdownload.soe.ucsc.edu arxiv.org genome.ucsc.edu www.gencodegenes.org bioconductor.org crossmap.readthedocs.io daler.github.io doi.org export.arxiv.org pyranges1.readthedocs.io pysam.readthedocs.io rest.ensembl.org www.ncbi.nlm.nih.gov

Hostnames that appear in the skill's files. Referencing a host is not a finding; compare against the findings above and the skill's stated purpose.

Package contents recorded 2026-10-22 at commit 593377bb0487. The scan above ran against the version current at scan time; the two can differ if the skill has since been updated.

What we checked

What we did not check

Sources